Application system for an active-ingredient release system, comprises a film-forming transparent plastic foil strip detachably connected to plaster containing an active ingredient and to controlled-release agent for the active ingredient

摘要

The application system for an active-ingredient release system, comprises a film-forming transparent plastic foil strip (2) detachably connected to a plaster (3) containing an active ingredient and to a controlled-release agent (6) for the active ingredient that is kept separate from the plaster by the film. The film-forming strip exhibits a folding line (5) and a detachable protective foil for covering the adhesive surface of the plaster. Width of the folding line corresponds to the width of the plaster. Length of the strip is a multiple of the length of the plaster. The application system for an active-ingredient release system, comprises a film-forming transparent plastic foil strip (2) detachably connected to a plaster (3) containing an active ingredient and to a controlled-release agent (6) for the active ingredient that is kept separate from the plaster by the film. The film-forming strip exhibits a folding line (5) and a detachable protective foil for covering the adhesive surface of the plaster. Width of the folding line corresponds to the width of the plaster. Length of the strip is a multiple of the length of the plaster. The controlled-release agent is permanently positionable on the active-ingredient containing surface (4) of the plaster after removal of the protective foil, detachable from the release agent and is permanently positionable along the folding line through refolding of the strip after removal of the protective foil. The plaster is directly applied on skin by removal of the strip. The plaster and the release agent are positioned on the same surface of the strip at a distance from the folding line and are covered by a detachable outer protective foil, which exhibits a peel-off aid. The peel-off aid is an attenuation line in the protective foil or is a part of the protective foil not connected with the remaining part of the foil. The protective foil of the plaster and/or the release agent is composed of different materials. In the case of a folding along the folding line, the two parts of the strip exhibit an identical length along the folding line. Part of the strip is detachably connected with the release agent, extends from the folding line and covers the entire surface of the release agent. The release agent is a divisible agent, a multilayer, impermeable for an active ingredient or an agent that retards the release of the active ingredient. The release agent comprises external detachable protective layers, an adhesive layer, an active ingredient barrier layer, further adhesive layer detachably connected with the strip, and combined active ingredient retarding adhesive layers that are detachably connected with the strip. The release agent is divisible over attenuation lines, perforation lines or cut lines and is divisible in such a manner that in each case 10-90 % of the active ingredient-containing surface of the plaster is coverable. The size of the impermeable active ingredient release agent corresponds in each case to 10-100 % of the active ingredient-containing surface of the plaster. The plaster exhibits an active ingredient-containing- reservoir or matrix. The application system is folded over the folding line and the folded system is packed in sterile-and gas-tight manner.