NEW USE OF PYRIMIDINE OR TRIAZIN-2-CARBONITRILES FOR THE TREATMENT OF CRANKS ASSOCIATED WITH CYSTEINE PROTEASE ACTIVITY AND NEW PYRIDIMIDINE-2-CARBONITRIL ACIDS

摘要

The present invention therefore provides use of a compound of formula (I) and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases S, K, F, L and B. Of particular interest are diseases associated with Cathepsin S. In addition, this invention also discloses processes for the preparation of such inhibitors.