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'death domain containing receptor 4 (dr4) - a member of the tnf receptor superfamilie, which trail (apo 2l) binds
'death domain containing receptor 4 (dr4) - a member of the tnf receptor superfamilie, which trail (apo 2l) binds
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机译:“含有受体4(dr4)的死亡域-tnf受体超家族的成员,其尾部(apo 2l)结合
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摘要
The present invention relates to novel Death Domain Containing Receptor-4 (DR4) proteins which are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR4 proteins. DR4 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of DR4 activity.
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