PALLADIUM CATALYST AND METHOD FOR PRODUCING BIARYL-BASED COMPOUND OR HETEROBIARYL-BASED COMPOUND USING IT

摘要

PROBLEM TO BE SOLVED: To provide a new, active palladium catalyst that enables a Suzuki-Miyaura coupling reaction in a small amount of use to proceed in a high yield under a mild reaction condition, and a method for producing a biaryl-based compound or a heterobiaryl-based compound using it.;SOLUTION: The palladium catalyst to be used in producing the biaryl-based compound by reacting an aromatic halide and an aromatic boronic acid in the presence of a palladium catalyst and a base is prepared by fixing palladium acetate dissolved in [1-butyl-3-methylimidazolium]PF₆ in a vacancy of amorphous alumina subjected to surface modification with a diethylaminopropyl residue.;COPYRIGHT: (C)2008,JPO&INPIT