METHOD FOR SELECTING EFFECTIVE GROUP FOR ADMINISTRATION OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORY AGENT OR ANGIOTENSIN RECEPTOR ANTAGONISTIC AGENT

摘要

PPROBLEM TO BE SOLVED: To provide a method for selecting patients effective in the administration of an angiotensin-converting enzyme inhibitory agent (ACE I) or angiotensin receptor antagonistic agent (ARB) for ameliorating the pregnosis of myocardial infarction-developed patients, and to provide a reagent and its kit useful for easily conducting the method. PSOLUTION: The method comprises the following procedure: for a subject's biological specimen, i.e. a patient in question, a genotype at the 1165th on the coding region of 1-adrenergic receptor gene (B1-AR gene) is detected, thus judging that the administration of ACE I or ARB is effective for ameliorating the prognosis of the patient's life when the genotype represents C (cytosine)'s homozygote. PCOPYRIGHT: (C)2008,JPO&INPIT