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FUNCTIONAL MOLECULE, AMIDIDE FOR SYNTHESIZING FUNCTIONAL MOLECULE AND TARGET MATERIAL-ANALYZING METHOD

机译:功能分子,用于合成功能分子的胺和目标材料分析方法

摘要

PPROBLEM TO BE SOLVED: To provide a functional molecule facilitating the amplification by PCR or the like even if two or more kinds of modified nucleotide units having different substituents are included, to provide an amidide for synthesizing the functional molecule usable for the synthesis of the functional molecule, and to provide a target material-analyzing method using them. PSOLUTION: The functional molecule contains a modified nucleotide unit to which a substituent is introduced so as to be eliminated from a base. The amidide for synthesizing the functional molecule used for the production of the functional molecule is obtained by introducing the substituent so as to be eliminable from the base. The target material-analyzing method including a random pool-making step for making a random pool of the functional molecules, a selection step for selecting a desired functional molecule, and an amplification step for amplifying the selected functional molecule further includes an eliminating step for eliminating the substituent from the selected functional molecule. PCOPYRIGHT: (C)2009,JPO&INPIT
机译:

要解决的问题:即使包含具有不同取代基的两种或更多种修饰的核苷酸单元,也要提供便于通过PCR等进行扩增的功能分子,以提供用于合成可用于合成的功能分子的酰胺。的功能分子,并提供使用它们的目标材料分析方法。

解决方案:功能分子包含修饰的核苷酸单元,在该核苷酸单元中引入了取代基以从碱基上消除。用于合成功能分子的酰胺是通过从碱基上消除取代基而引入的,从而获得用于合成功能分子的酰胺。靶物质分析方法包括用于随机形成功能分子的随机池形成步骤,用于选择期望的功能分子的选择步骤以及用于放大所选择的功能分子的扩增步骤,还包括消除步骤。来自所选功能分子的取代基。

版权:(C)2009,日本特许厅&INPIT

著录项

  • 公开/公告号JP2008230985A

    专利类型

  • 公开/公告日2008-10-02

    原文格式PDF

  • 申请/专利权人 FUJITSU LTD;

    申请/专利号JP20070069378

  • 发明设计人 FUJIWARA KENJI;FUJITA SHOZO;

    申请日2007-03-16

  • 分类号C07H21/04;C07H19/173;G01N33/566;C12N15/09;

  • 国家 JP

  • 入库时间 2022-08-21 20:24:41

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