POLYMORPHIC CRYSTAL OF 4'-{2-(1S, 2R)-2-HYDROXY-2-(4-HYDROXYPHENYL)-1-METHYLETHYLAMINOETHOXY}-3-ISOPROPYL-3', 5'-DIMETHYLBIPHENYL-4-CARBOXYLIC ACID HYDROCHLORIDE

摘要

PROBLEM TO BE SOLVED: To provide crystals of a salt of 4'-{2-[(1S, 2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethylamino]ethoxy}-3-isopropyl-3', 5'-dimethylbiphenyl-4-carboxylic acid.;SOLUTION: The α type, β type and γ type crystals produced by treating hydrochloride of 4'-{2-[(1S, 2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl-amino]ethoxy}-3-isopropyl-3', 5'-dimethylbiphenyl-4-carboxylic acid with specified solvents, which can be discriminated by the characteristic diffraction peaks of powder X-ray diffractometry and the like.;COPYRIGHT: (C)2008,JPO&INPIT