Using HMGB1 for wound healing

摘要

The present invention specifically describes the role of HMGB1 in improving wound healing in a diabetes model. Effects of glycyrrhizin, reduced expression of HMGB1 in skin and fibroblasts of diabetic patients, accumulation of rage in skin of diabetic mice, and based on the chemical induction effect of HMGB1 on normal and diabetic human cells Other evidence shows that HMGB1 is advantageously available for the preparation of medications specifically directed to the healing of wounds in diabetics.