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Nn-acyloxypropyl lysine methyl ester type and N, N-bis (n-acyloxypropyl) lysine methyl ester type compounds and use of the compounds as surfactants having antibacterial activity

机译:N-酰氧基丙基赖氨酸甲酯型和N,N-双(n-酰氧基丙基)赖氨酸甲酯型化合物以及该化合物作为具有抗菌活性的表面活性剂的用途

摘要

The invention relates to novel compounds having an amphiphilic character (cationic, anionic, amphoteric and non-ionic), derivatives of n acyloxypropyl-type lysine amino acid according to general formula (I), which are intended to be used in the food, pharmaceutical and cosmetic industries as surface-active agents having a self-aggregating capacity and antimicrobial properties. Variations in activity are a function of the ionic nature of the final molecule, the number of fatty chains and the length thereof. The aforementioned products are prepared using a chemical synthesis method. The intermediate and final products are purified by means of liquid/liquid and liquid/solid extractions, crystallisations, cationic exchange chromatography and normal phase chromatography.
机译:本发明涉及具有两亲特性的新型化合物(阳离子,阴离子,两性和非离子性),根据通式(I)的正酰氧基丙基型赖氨酸氨基酸的衍生物,其旨在用于食品,药品中作为表面活性剂,具有自聚集能力和抗菌性能,以及化妆品工业。活性的变化是最终分子的离子性质,脂肪链的数量及其长度的函数。上述产物是使用化学合成方法制备的。中间产物和终产物通过液/液和液/固萃取,结晶,阳离子交换色谱法和正相色谱法纯化。

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