Of administration of rapamycin analogues with medical equipment for obtaining long-term efficacy and composition

摘要

In comparison with paclitaxel and rapamycin systems, compositions and systems containing low zotarolimus is disclosed the degree of inflammation of a safe, effective, resulting. This is a medical device having a support structure that can support or excipient or pharmaceutically acceptable carrier, it can be a carrier or excipient includes substances or one or more therapeutic agents, and surface Carriers There is a coating on, for example, the coating comprises a therapeutic compound such as pharmaceuticals. The support structure for medical devices, coronary stents used in the vasculature, peripheral stents, catheters, arterio-venous grafts, bypass grafts, and the like drug delivery balloon. These compositions and agents that inhibit anti-proliferative agents, anti-platelet agents, anti-inflammatory agents, antithrombotic agents, cytotoxic agents, chemokine binding or cytokines, cell de-differentiation inhibitors, antilipidemic agents, system, matrix It can metalloprotease inhibitor, used in combination with other agents such as a combination of these and other agents or cytostatic agents.