Expression of the carboxyl polypeptide - gamma in the host system which is defective in carboxylation - gamma

摘要

The present invention relates to a novel method for preparing gamma-carboxylated poly-peptides, including coagulation Factors VII, IX, X and Protein C. The present invention also relates to novel host cells and recombinant vectors to be used in this improved method for preparing gamma-carboxylated polypeptides.