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Regulation of telomere length and cancer therapy in telomerase positive cells
Regulation of telomere length and cancer therapy in telomerase positive cells
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机译:端粒酶阳性细胞中端粒长度的调节和癌症治疗
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摘要
Induction of telomere shortening, G2 arrest and apoptosis in telomerase positive cancer cells using acyclic nucleoside analogs has been disclosed. In addition, methods for impairment or prevention of tumorigenic telomerase positive cells from having a chance to grow into a tumor and methods for promoting tumor regression (decrease in size of an established tumor) using acyclic nucleoside analogs has been disclosed.
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