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Catalytic production of hydrocodone, hydromorphone and derivatives thereof

机译:氢可酮,氢吗啡酮及其衍生物的催化生产

摘要

A method for the catalytic production of hydrocodone derivatives and hydromorphone derivatives, respectively, utilizing a transition metal catalyst of the formula [M(PRSUP4/SUPRSUP5/SUPRSUP6/SUP)SUBn/SUBXSUBm/SUB]SUBp/SUB; wherein M is a Group VIII transition metal; RSUP4/SUP, RSUP5/SUP and RSUP6/SUP are selected from the group consisting of alkyl, aryl, alkoxyl, phenoxyl and combinations thereof; X is a halide or an anion; n is 1, 2, 3 or 4; m is 1 or 2; and p is at least 1.
机译:一种利用式[M(PR 4 R 5 R 6 <]的过渡金属催化剂分别催化生产氢可酮衍生物和氢吗啡酮衍生物的方法/ SUP>) n X m ] p ;其中M是VIII族过渡金属; R 4 ,R 5 和R 6 选自烷基,芳基,烷氧基,苯氧基及其组合; X为卤化物或阴离子; n为1、2、3或4; m为1或2;并且p至少为1。

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