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EVALUATION METHOD FOR SKIN BARRIER FUNCTION RESTORING AGENT, AND EVALUATION KIT

机译:皮肤屏障功能恢复剂的评估方法及评估套件

摘要

PROBLEM TO BE SOLVED: To provide a novel evaluation method for skin barrier function restoring agent, capable of simply, quickly and surely evaluating whether a compound has skin barrier function restoring effects, and to provide an evaluation kit.;SOLUTION: The size of the ribosome in the ribosome solution, which is prepared by adding a compound that serves as a candidate for skin barrier function restoring agent, is used as an index and is evaluated in that skin barrier function restoring effect is higher, the smaller size of ribosome is. The ribosome solution can be produced by drying and solidifying a film-forming solution comprising a phospholipid solution for forming a film, and adding a buffer solution to this film, prior to the addition of the compound that serves as the candidate for the skin barrier function restoring agent.;COPYRIGHT: (C)2008,JPO&INPIT
机译:要解决的问题:提供一种新型的皮肤屏障功能恢复剂评估方法,能够简单,快速且确定地评估化合物是否具有皮肤屏障功能恢复作用,并提供评估工具包。核糖体溶液中的核糖体是通过添加作为皮肤屏障功能恢复剂候选物的化合物制备的核糖体溶液,该核糖体被用作指标,并且评估为,核糖体尺寸越小,皮肤屏障功能恢复效果越高。核糖体溶液可以通过如下方法制备:干燥并固化包含用于形成膜的磷脂溶液的膜形成溶液,并在该膜中添加缓冲溶液,然后添加用作皮肤屏障功能候选物的化合物。修复剂。; COPYRIGHT:(C)2008,JPO&INPIT

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