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Pyrazole derivatives for the treatment of conditions mediated by activated receptor activation of adenosine A2B or A3 receptors

机译:吡唑衍生物,用于治疗由腺苷A2B或A3受体的活化受体激活介导的疾病

摘要

Compounds of formula I in free or salt form, wherein RSUP1/SUP, RSUP2/SUP, RSUP3 /SUPand RSUP4 /SUPhave the meanings as indicated in the specification, are useful for treating a condition mediated by activation of the adenosine A2b receptor or the adenosine A3 receptor, particularly an inflammatory or obstructive airways disease. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
机译:游离形式或盐形式的式I化合物,其中R 1 ,R 2 ,R 3 和R 4 具有说明书中所指的含义,可用于治疗由腺苷A2b受体或腺苷A3受体活化介导的疾病,特别是炎性或阻塞性气道疾病。还描述了包含所述化合物的药物组合物和制备所述化合物的方法。

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