LIGAND ANALYZING METHOD DUE TO LOCALIZED SURFACE PLASMON RESONANCE METHOD AND MASS ANALYZING METHOD, AND SENSOR ELEMENT THEREFOR

摘要

PROBLEM TO BE SOLVED: To provide a ligand analyzing method capable of simply performing the analyzing operation of the ligand bonded to a certain substance by mass analysis with high sensitivity and higher reproducibility, and a sensor element therefor.;SOLUTION: The ligand analyzing method includes processes of: bringing the selective coupling substance on the sensor element, which is equipped with a substrate, a plurality of nanosize metal regions provided on the substrate and the selective coupling substance fixed on the nanosize metal regions, into contact with the ligand selectively coupled to the selective coupling substance in a sample to be inspected; measuring the coupling of the selective coupling substance with the ligand by a localized surface plasmon resonance method; and applying the sensor element to the mass analyzing method as it is to perform the mass analysis of the ligand.;COPYRIGHT: (C)2008,JPO&INPIT