Antibodies selective for tumor necrosis factor-related apoptosis-inducing ligand receptors and uses thereof

摘要

An isolated nucleic acid is disclosed which comprises a nucleic acid sequence encoding a heavy chain of an antibody, wherein the heavy chain of the antibody comprises (i) SEQ ID NO:25 or a functional equivalent thereof, (ii) SEQ ID NO:26 or a functional equivalent thereof, and (iii) SEQ ID NO:27 or a functional equivalent thereof.