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Meltlin

机译:麦特林

摘要

The purpose of the present invention is to provide a novel protein involved in adhesion and fusion between myoblasts in the course of the formation of byotube. The present invention relates to Meltrins, which a membrane protein having fusion, adhesion and aggregation activity of cells, especially myoblast; and to polypeptides of their domains, DNAs encoding them, antisense RNA for these DNAs, various antibodies to Meltrins and the polypeptides of their domains, expression vectors containing these DNAs, and transfomants by these vectors; as well as to the process for producing Meltrins and the polypeptides of their domains using those transformants and medical compositions comprising Meltrins or antagonist against them as an effective ingredient. IMAGE
机译:本发明的目的是提供一种新型蛋白质,其在byotube形成过程中参与成肌细胞之间的粘附和融合。本发明涉及Meltrins,它是一种具有细胞,特别是成肌细胞的融合,粘附和聚集活性的膜蛋白。以及其结构域的多肽,编码它们的DNA,这些DNA的反义RNA,抗Meltrins的各种抗体及其结构域的多肽,含有这些DNA的表达载体以及这些载体的转化子;以及使用这些转化子和包含Meltrins或针对它们的拮抗剂的药物组合物生产Meltrins及其结构域多肽的方法。 <图像>

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