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Cleavage of VEGF and VEGF receptors by wild type and mutant MT-SP1
Cleavage of VEGF and VEGF receptors by wild type and mutant MT-SP1
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机译:野生型和突变MT-SP1对VEGF和VEGF受体的切割
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摘要
MT-SP1 mutein proteases with altered specificity for the target molecules they cleave can be used to treat human diseases, such as cancer. Cleaving VEGF or VEGFR at certain substrate sequences with wild-type and mutein MT-SP1 proteases can be used to treat pathologies associated with angiogenesis.
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