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Blood purification device using the same, and hollow fiber membrane for blood purification

机译:使用该血液净化装置的血液净化装置以及中空纤维膜用于血液净化

摘要

An object of the present invention is to provide a hollow fiber membrane with enhanced phosphorus-removing performance without impairing antithrombogenicity in order to inhibit in vivo accumulation of phosphate ions in living body that might cause bone metabolism disorders. The present inventors have found that a hollow fiber membrane having a specific membrane structure and a specific membrane composition possesses a very useful range for inner surface charges of the membrane. More particularly, the inventors have discovered that the above object can be achieved in a limited range in which the zeta potential on the inner surface of a hollow fiber membrane measured under given certain conditions is greater than -3.0 mV but less than 0 mV. This finding has led to the completion of the present invention.
机译:本发明的目的是提供一种中空纤维膜,该中空纤维膜具有增强的除磷性能而不损害抗血栓形成性,从而抑制可能导致骨代谢紊乱的生物体内磷酸根离子的积累。本发明人发现具有特定膜结构和特定膜组成的中空纤维膜具有非常有用的膜内表面电荷范围。更特别地,发明人发现可以在有限的范围内实现上述目的,其中在给定的特定条件下测量的中空纤维膜的内表面上的ζ电位大于-3.0mV但小于0mV。该发现导致完成本发明。

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