Optical activity production manner of hydroxymethyl displacement phenylalanine

摘要

This invention, reducing the cyano displacement benzylidene hydantoin (1), the aminomethyl displacement benzyl hydantoin (2) or that salt profit, next the said aminomethyl displacement benzyl hydantoin (2) or converting the amino group of that salt to hydroxyl group, the hydroxymethyl displacement benzyl hydantoin (3) profit, and treating the said hydroxymethyl displacement benzyl hydantoin (3) with the enzyme, the D- hydroxymethyl displacement phenylalanine (4a) or that salt, or the L- hydroxymethyl displacement phenylalanine (4b) or obtains that salt, optical activity it is production manner of the hydroxymethyl displacement phenylalanine. According to this invention, optical activity can obtain the hydroxymethyl displacement phenylalanine simply on an industrial scale it is possible to offer the production manner which.