Peroxisome proliferator-responsive receptor (PPAR) activator, and medicament, supplement, functional food and food additive using the same

摘要

Provided is a peroxisome proliferator-activated receptor (PPAR) activator that can be taken for a long period of time without the problem of side effects and does not have a specific flavor. Nobiletin is used as a PPAR activator. Nobiletin has an excellent PPAR activity and an excellent adiponectin secretion promoting effect, and is contained in a large amount in citrus fruits, in particular, Shikuwasha, a specialty of Okinawa (citrus depressa HAYATA), and citrus fruits have been eaten for many years. There is no problem with sex and the calorie is low, so it can be taken for a long time. In addition, nobiletin is tasteless and odorless, so even if it is added to food, it does not harm the flavor unique to the food, and therefore can be added to food and taken.