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Screening method of Hyphomycetes unique anti-bacterial medicine and kit for that

机译:疏水菌独特的抗菌药物的筛选方法及试剂盒

摘要

Long-cherished desire invention has designated that efficient screening method of agricultural chemical candidacy or medicine candidacy is offered as topic. Concrete, furthermore without using the plant body concerning the agricultural chemical, it designates that the agricultural chemical candidacy chemical compound which does not have the times when it causes the harmful influence to other living thing such as plant is done, the screening efficiently as topic. The long-cherished desire inventor et. al the Hyphomycetes biologically is the close relation with the gene manifestation vector which the Hyphomycetes unique enzyme the cord/code is done, but character it converts the yeast which the particular enzyme the possession is not done, the control yeast (the yeast which does not reveal the Hyphomycetes unique enzyme) and it applies the agricultural chemical candidacy sample to the Hyphomycetes unique enzyme revelation transformant, on the control yeast does not produce the effect of the side effect, and the like it succeeds in developing the screening method of selecting the agricultural chemical candidacy sample where uniquely shows growth obstruction or bactericidal action in only the Hyphomycetes unique enzyme revelation transformant, as agricultural chemical candidacy,Long-cherished desire invention was made to complete. Furthermore, to use in the same way to also the screening of medicine candidacy it is possible this screening method.
机译:长期以来的期望发明指定了提供有效的农业候选资格或药物候选资格筛选方法。另外,在不使用农药的植物体的情况下,将没有对植物等其他生物造成有害影响的时期的农药候选化合物作为混凝土进行有效筛选。渴望已久的发明家等。菌丝在生物学上与菌丝/密码完成的菌丝独特酶的基因表达载体有密切关系,但其特性是将酵母所拥有的特定酶转化为酵母,而对照酵母(不含有酵母)揭示了Hyphomycetes独特的酶),并将农业化学候选样品应用于Hyphomycetes独特的酶揭示转化体,在对照酵母上不产生副作用的作用,并成功地开发了选择农作物的筛选方法化学候选物,仅在菌丝体独特的酶揭示转化体中独特地显示出生长障碍或杀菌作用,作为农用化学候选物,完成了长期以来所希望的发明。此外,以同样的方式也用于筛选候选药物时,这种筛选方法是可能的。

著录项

  • 公开/公告号JPWO2005085416A1

    专利类型

  • 公开/公告日2008-01-24

    原文格式PDF

  • 申请/专利权人 独立行政法人理化学研究所;

    申请/专利号JP20060510821

  • 发明设计人 工藤 俊章;本山 高幸;

    申请日2005-03-04

  • 分类号C12N1/19;C12Q1/06;C12N15/09;G01N33/15;G01N33/50;

  • 国家 JP

  • 入库时间 2022-08-21 20:16:59

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