Bioadhesive microspheres, as well as their use in drug delivery and imaging systems

摘要

(57) or bio-adhesive polymer, in the form of microcapsules containing the purpose of diagnosis or treatment of diseases of the [summary] gastrointestinal tract, the biological activity or substrate drug, bioadhesive as a coating of the microcapsules I described for the polymer. All of this polymeric microspheres having a bioadhesive force 11mN / cm ² of (110N / m ²⁾ at least. I is also described technique for the creation of bioadhesive microspheres and for measuring bioadhesive forces between the selected segments of the gastrointestinal tract and microspheres in vitro. (On the other hand,) to establish the chemical nature, the surface morphology, and the drug-loaded microspheres sizes, the correlation with the strength adhesive biological (on the other), the quantitative method, the natural and synthetic polymers in the large group relatively , from theoretical consideration, subscription most promising material to be used to create a bioadhesive microspheres - to provide a means of cleaning.