Methods and Compositions for Inferring Eye Color and Hair Color

摘要

Methods for inferring eye color or eye shade of an individual from a nucleic acid sample of the individual by detecting the nucleotide occurrence of an eye color related single nucleotide polymorphism (SNP) as set forth in SEQ ID NOS: 1 to 7 and, optionally, SEQ NOS:8 to 10 and/or SEQ ID NOS:26 to 48, are provided. Also provided are methods for inferring hair color or hair shade of an individual from a nucleic acid sample of the individual by detecting the nucleotide occurrence of a hair color related SNP as set forth in SEQ ID NOS: 11 to 25. Methods for inferring eye color/shade and/or hair color/shade of an individual from a protein sample of the individual by detecting an amino acid residue encoded by the nucleotide occurrence of an eye color related SNP or a hair color related SNP, respectively, also are provided. In addition, compositions, including oligonucleotides and antibodies, useful for practicing such methods are provided, as are kits for performing the methods.