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Anti human ovarian cancer-anti CD3 bispecific antibody

机译:抗人卵巢癌-抗CD3双特异性抗体

摘要

The present invention provides an anti-ovarian cancer bispecific antibody. Said antibody includes two polypeptide domains connected by a polypeptide linker, one is anti-ovarian cancer antibody, or its Fab fragment, single complementarity determining region (CDR) antibody or single chain Fv (scFv) and the other is anti-CD3 antibody, or its Fab fragment, single CDR antibody or scFv. The present invention also provides DNA sequences encoding said antibody, an expression vector containing said DNA sequence, and a host cell containing said expression vector.
机译:本发明提供了抗卵巢癌双特异性抗体。所述抗体包括通过多肽接头连接的两个多肽结构域,一个是抗卵巢癌抗体或其Fab片段,单互补决定区(CDR)抗体或单链Fv(scFv),另一个是抗CD3抗体,或其Fab片段,单CDR抗体或scFv。本发明还提供了编码所述抗体的DNA序列,包含所述DNA序列的表达载体和包含所述表达载体的宿主细胞。

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