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Feeding Chamber, an Apparatus and a Method for Production of Doses of Dry Powder, a Method for Controlling Particle Segregation in Dry Powder During Filling
Feeding Chamber, an Apparatus and a Method for Production of Doses of Dry Powder, a Method for Controlling Particle Segregation in Dry Powder During Filling
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机译:进料室,设备和生产干粉剂量的方法,控制填充过程中干粉中颗粒偏析的方法
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摘要
A method and an apparatus for exact metering and volumetric filling of dry powder medicament doses into preformed containers, which are adapted for administration by a dry powder inhaler. The filling apparatus includes at least a bulk powder source, a feeding chamber, and a receptacle providing the volume for a specified load mass of dry powder. The bulk powder source releases a portion of powder discontinuously to the feeding chamber, but is disconnected from the feeding chamber and receptacle during the filling operation. The filling apparatus further presents a plane surface in contact with the movable feeding chamber and provides a hard-wearing, low friction coating for reducing dynamic friction and powder retention.
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