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SYSTEMS AND METHODS OF COATING A HYBRID CAROTID BYPASS VASCULAR GRAFT IN A MAMMAL
SYSTEMS AND METHODS OF COATING A HYBRID CAROTID BYPASS VASCULAR GRAFT IN A MAMMAL
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机译:在哺乳动物中通过血管移植物涂覆混合颈动脉的系统和方法
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摘要
Hybrid synthetic grafts and embodiments of systems and methods for producing hybrid vascular grafts that can yield implantable grafts that combine synthetic grafts with living cells. Embodiments of systems can include a pressure/flow loop subsystem having an external flow loop system coupled to a specimen holders where the pressure/flow loop subsystem is capable of adjusting at least two dynamic conditions in the specimen holder or a diameter of a specimen in the specimen holder. Embodiments of methods can coat a hybrid carotid bypass vascular graft with a confluent monolayer of endothelial cells by immobilizing a plurality of endothelial cells on the hybrid carotid bypass vascular graft and placing the hybrid carotid bypass vascular graft in a system embodiment according to the invention under conditions effective to promote the endothelial cells to form a confluent monolayer on the surface of the hybrid vascular graft.
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