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Substituted benzimidazole compounds with dual NOS inhibitory activity and mu opioid agonist activity
Substituted benzimidazole compounds with dual NOS inhibitory activity and mu opioid agonist activity
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机译:具有双重NOS抑制活性和μ阿片类激动剂活性的取代苯并咪唑化合物
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摘要
The present invention relates to benzimidazole compounds having dual nitric oxide synthase (NOS) inhibitory activity and agonist activity at the mu-opioid receptor, to pharmaceutical and diagnostic compositions containing them, and to their medical use, particularly as compounds for the treatment or prevention of chronic pain, acute pain, migraine, and neuropathic pain.
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