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High-Cell Density Fed-Batch Fermentation Process for Producing Recombinant Protein
High-Cell Density Fed-Batch Fermentation Process for Producing Recombinant Protein
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机译:高细胞密度补料分批发酵生产重组蛋白
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摘要
Methods for producing proteins, for example, recombinant meningococcal 2086 proteins, using fed-batch fermentation with continuous input of an inducer after achieving a threshold parameter, and optionally continuous input of a carbon source, for example, a constant rate input, to improve protein yields, as well as high density protein compositions and compositions for use in the methods of the present invention, are provided.
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