METHOD FOR DEVELOPING CULTURE MEDIUM USING GENOME INFORMATION AND IN SILICO ANALYSIS

摘要

A method for developing a culture medium using genome information and in silico anlaylsis. In one implementation, the method involves developing a minimal synthetic medium, including the steps of constructing a metabolic network using genome information of prokaryotic cell or eukaryotic cell, selecting components of the minimal synthetic medium removing any one among external metabolites from the constructed metabolic network and conducting metabolic flux analysis using in silico simulation, and determining a final culture medium by actual culture.