首页>
外国专利>
PTU COMPOUNDS FOR PROMOTING THE IN VITRO CULTURE OF (HIGHLY PIGMENTED) MELANOCYTES
PTU COMPOUNDS FOR PROMOTING THE IN VITRO CULTURE OF (HIGHLY PIGMENTED) MELANOCYTES
展开▼
机译:用于促进(高色素)黑色素细胞体外培养的PTU化合物
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method for promoting the in vitro multiplication of human melanocytes and/or the freezing thereof, notably human melanocytes obtained from individuals of phototype IV, V or VI or from hyperpigmentary lesions entails introducing into a culture of same, a thus effective amount of at least one 1-phenyl-3-(2-thiazolyl)-2-thiourea (PTU) compound or PTU analogue or PTU mimetic selected from the group consisting of vitamin C, arbutin, hydroquinone, kojic acid or acid or ester derivative thereof, ellagic acid, aminophenol derivative, procysteine or derivative thereof, niacinamide, isothiocyanate, thiocyanate, lucinol and mixtures thereof; also provided thereby can be melanocyte libraries, co-cultures and reconstructed epidermides and/or reconstructed skin that are highly pigmented which are useful for the study of pigmentation disorders, for the screening of cosmetic or dermatological active agents, or for the treatment of skin lesions, in particular in individuals with a high phototype.
展开▼