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Advanced cell-transducing transport domain-target protein-transport domain fusion protein and uses thereof
Advanced cell-transducing transport domain-target protein-transport domain fusion protein and uses thereof
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机译:先进的细胞转导转运域-靶蛋白-转运域融合蛋白及其用途
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摘要
The present invention provides a fusion protein which delivers a functional protein or peptide into a cell at enhanced efficiency. The fusion protein of the present invention is a transduction domain-target protein-transduction domain fusion protein, wherein the transduction domain, which comprises 6-12 amino acid residues whose more than ¾ consist of arginine or lysine residues, is covalently bonded to each of the amino- and carboxyl-terminal ends of the target protein. Green fluorescence protein and Cu/Zn-superoxide dismutate (SOD) are used as the target protein.
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