embedded image "/> Pyridinalkyl-aminoalkyl-IH-indole derivatives having an inhibitory action on 5-HT and serotonin reuptake as antidepressants and anxiolytics
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Pyridinalkyl-aminoalkyl-IH-indole derivatives having an inhibitory action on 5-HT and serotonin reuptake as antidepressants and anxiolytics

机译:对5-HT和5-羟色胺再摄取具有抑制作用的吡啶烷基-氨基烷基-IH-吲哚衍生物作为抗抑郁药和抗焦虑药

摘要

Novel indole derivatives of the formula (I), in which X, Y, R1, R1′, m and n have the meanings indicated in Patent Claim 1, have a strong affinity to the 5-HT1A and in some cases to the 5-HT1D receptors. The compounds inhibit serotonin reuptake, exhibit serotonin-agonistic and -antagonistic properties and are suitable as antidepressants, anxiolytics and for the treatment of neurodegenerative diseases; embedded image
机译:式(I)的新颖的吲哚衍生物,其中X,Y,R 1 ,R 1',m和n具有专利权利要求1中所示的含义,具有与5-HT 1A 以及在某些情况下与5-HT 1D 受体具有很强的亲和力。该化合物抑制5-羟色胺再摄取,表现出5-羟色胺的激动和拮抗特性,并适合用作抗抑郁药,抗焦虑药和用于神经退行性疾病的治疗。 “嵌入式图像”

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