A Molecule isolated polynucleotide comprising a DNA Sequence encoding a Molecule of RNA that encodes an infectious virus and PRRS Vaccine Transfected Cell.

摘要

An isolated polynucleotide molecule characterized in that it comprises a DNA sequence encoding an infectious RNA molecule encoding a North American PRRS virus that is genetically engineered such that it comprises one or more heterologous antigenic epitopes, where the DNA sequence encoding the molecule RNA that encodes the North American PRRS virus is SEQ ID. No. 1 o is the sequence beginning with and ranging from nucleotide 1 to including nucleotide 15416 of SEQ ID. No. 1;However, the nucleic acid related to seq-1-12622 nuclear power plant is one of adenosine and nucleoside related to seq-1559 nuclear power plant. ID.1. Is a rudder, not a cytotoxemia, but includes one or more additional nucleoside sequences, which encode different antigen entries, in which each heteroantigen entry can promote an effective immune response to a specific disease source in mammals or birds. It also describes a blood transfusion host cell and a vaccine.