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Solid Particles to obtain a Compressible, procedures and procedures for using the Solid Particles in tablets or Tablets For Body Hygiene

机译:获得可压缩的固体颗粒,在片剂或用于人体卫生的片剂中使用固体颗粒的程序和步骤

摘要

Solid Compressible particles that comprise between 20 and 38% by weight of an oily liquid or viscous, between 50 and 70% by weight of a polymer of Cellulose and between 2 and 15% by weight of a Hydrophobic Compound coating, wherein Said particles have a size less than or equal to 180 microns.For example, the Oily liquid or viscous, can be a Vegetable Oil or a Surfactant such as cocoamido Propyl Betaine, cocamide DEA, and mixtures thereof. The Polymer can be Carboxymethyl Cellulose, microcrystalline Cellulose, or mixtures thereof.The hydrophobic coating composition can be SILICON DIOXIDE, Calcium phosphate, Magnesium carbonate, aluminium oxide. Solid Compressible particles ranging between 50 and 70 wt% of a Crystalline alcohol, between 25 and 45% by weight of a polymer of Cellulose and between 5 and 18% by weight of a Hydrophobic Compound Coating.For example, The alcohol can be a polyol such as Crystalline xylitol, sorbitol, maltitol, isomalt, Hydroxy Starch; a terpene such as thymol, carvacrol, or Menthol. Particles are used to produce Tablets or Tablets for Personal Hygiene in a quantity between 1 and 16% by weight of the total weight of the tablet or tablet.
机译:固体可压缩颗粒,其包含20至38重量%的油状液体或粘性,50至70重量%的纤维素聚合物和2至15重量%的疏水化合物涂层,其中所述颗粒具有尺寸小于或等于180微米。例如,油性液体或粘性油可以是植物油或表面活性剂,例如椰油酰胺基丙基甜菜碱,椰油酰胺DEA及其混合物。聚合物可以是羧甲基纤维素,微晶纤维素或它们的混合物。疏水涂料组合物可以是二氧化硅,磷酸钙,碳酸镁,氧化铝。固体可压缩颗粒,其含量为结晶醇的50%至70%(重量),纤维素聚合物的25%至45%(重量)和疏水化合物涂层的5%至18%(重量)。例如,醇可以是多元醇如结晶木糖醇,山梨糖醇,麦芽糖醇,异麦芽糖醇,羟淀粉;萜烯,例如百里香酚,香芹酚或薄荷醇。颗粒用于生产个人卫生用片剂或片剂,其量为片剂或片剂总重量的1至16重量%。

著录项

  • 公开/公告号AR058580A1

    专利类型

  • 公开/公告日2008-02-13

    原文格式PDF

  • 申请/专利权人 MAKUC RUBEN ANTONIO;MUMOLI JOSE ALEJANDRO;

    申请/专利号AR2006P105647

  • 发明设计人

    申请日2006-12-20

  • 分类号A61K7/00;A61K7/06;A61K7/075;A61K7/16;A61K7/48;A61K7/50;

  • 国家 AR

  • 入库时间 2022-08-21 20:08:57

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