Process for the preparation of a compound Intermediate in the synthesis of a Derivative of a steroid 9 - 11epoxi; a Derivative of mexrenona; of (Delta) - 4,5 3 Keto steroid replaced with 7alfa alcoxicarbonilo and other intermediaries and substrates and compounds thereof are obtained

摘要

Claim 1, a process for the preparation of a Compound, Intermediate in the synthesis of a Derivative of a steroid 9-11 epoxy, wherein Said Compound of Formula 1 where is - - - - - chr5 represents the Group chr4 - or - CR4 = CR5; R3, R4 and R5 are selected independently the Group form Hydrogen or lower alkyl, Halo, Hydroxy, alkoxy, Lower hidroxialquilo alkoxyalkyl esters,,,Hydroxy and carbonyl cyano ariloxi; r1 represents a radical alcoxicarbonilo or hidroxicarbonilo Lower Alpha oriented; - B - B - - - chr7 chr6 represents the group or a Group - oriented formula Alpha or beta (2) where R6 and R7 is independently selected from the group consisting of hydrogen, Halo, alcox I Lower hidroxialquilo, acyl, alkyl alcoxicarbonilo alkoxyalkyl esters, hidroxicarbonilo,,,Aciloxialquilo, ciano and ariloxi; and R8 and R9 are selected independently from the group consisting of hydrogen, Hydroxy, Halo, Lower alkoxy, acyl, hidroxialquilo, hidroxicarbonilo, alcoxicarbonilo alkoxyalkyl esters, alkyl, cyano, or aciloxialquilo, and ariloxi, R8 and R9 together constitute a str To carbocu00edclico or Heterocyclic ring,R8 and R9 with R6 and R7 or comprise a Ring Structure carbocu00edclico or Heterocyclic FUSED pentacyclic Ring D; in which the said process comprises: deleting a leaving Group 11 Alpha of a compound of formula 4: where R2 is a leaving Group 11 Alpha whose Abstraction is effective P To generate a double ligation between 9 and 11 Carbon Atoms.