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solid oral pharmaceutical dosage form, process for preparing an oral pharmaceutical dosage form, method for improving inhibition of gastric acid secretion, and use of a pharmaceutical dosage form
solid oral pharmaceutical dosage form, process for preparing an oral pharmaceutical dosage form, method for improving inhibition of gastric acid secretion, and use of a pharmaceutical dosage form
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机译:固体口服药物剂型,制备口服药物剂型的方法,改善对胃酸分泌的抑制的方法以及药物剂型的用途
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ORAL SOLID PHARMACEUTICAL DOSAGE FORM, PROCESS FOR PREPARING AN ORAL PHARMACEUTICAL DOSAGE FORM, METHOD FOR IMPROVING GASTRIC ACID SECRECTION, AND USING A PHARMACEUTICAL DOSAGE FORM. A solid oral pharmaceutical dosage form comprising an acid sensitive proton pump inhibitor (PPI) as a single active drug which releases PPI in two separate pulses, one immediate and one delayed. PPI is formulated as a core material in the form of tablets which are coated, inter alia, with a combination of a delayed release modification layer and a delay time control layer, which together achieve release properties. beneficial. The tablets are further provided with an enteric coating layer. The application also relates to processes for the preparation of dosage forms as well as their use in the treatment of gastrointestinal disorders.
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