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The pig as a preclinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosage forms: a PEARRL review

机译：猪作为预测口腔生物利用度的临床前模型，并在药物口腔剂型的体内表现：Pearrl审查

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Laura J Henze; Niklas J Koehl; Joseph P OShea; Edmund S Kostewicz; René Holm; Brendan T Griffin;
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1. The pig as a preclinical model for predicting oral bioavailability and in?vivo performance of pharmaceutical oral dosage forms: a PEARRL PEARRL review [J] . Henze Laura J., Koehl Niklas J., OShea Joseph P., Journal of Pharmacy and Pharmacology . 2019,第4期

机译：猪作为预测口腔生物利用度的临床前模型，以及药物口腔剂量形式的体内性能：Pearrl Pearrl评论
2. A review of patient-specific gastrointestinal parameters as a platform for developing in vitro models for predicting the in vivo performance of oral dosage forms in patients with Parkinson’s disease [J] . Erik Wollmer, Sandra Klein International Journal of Pharmaceutics . 2017,第1期

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3. A novel in vivo predictive dissolution testing coupled with a modeling and simulation for hydrogel matrix monolithic extended release oral dosage forms [J] . Kambayashi Atsushi, Dressman Jennifer B. European journal of pharmaceutical sciences . 2019,第期

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4. Influence of Particle Size on Bioavailability and Rate of Absorption For Oral Dosage Forms Prepared From Poorly Water Soluble Drugs: A Comparison Between in-silico, in-vitro and invivo Pharmacokinetic Data. [C] . Annual meeting exposition of the Controlled Release Society . 2009

机译：粒度对水溶性药物不良制备的口服剂型生物利用度的影响及其吸收率：硅，体外和Invivo药代动力学数据的比较。
5. Understanding curing of ethylcellulose film coating and in vitro in vivo performance of oral dosage forms with scientific regulatory implications on biowaiver. [D] . Lin, Zhongqiang. 2015

机译：了解乙基纤维素薄膜包衣的固化和口服剂型的体外体内性能，对生物豁免具有科学的监管意义。
6. Oral diacetylmorphine (heroin) yields greater morphine bioavailability than oral morphine: bioavailability related to dosage and prior opioid exposure [O] . Ulrike Halbsguth, Katharina M Rentsch, Dominique Eich-Höchli, 2008

机译：口服二乙酰吗啡（海洛因）比口服吗啡产生更高的吗啡生物利用度：与剂量和先前的阿片类药物暴露有关的生物利用度
7. In vitro models for the prediction of in vivo performance of oral dosage forms [O] . Kostewicz Edmund S, Abrahamsson Bertil, Brewster Marcus, 2014

机译：预测口服剂型体内性能的体外模型
8. Guidance for Industry. Waiver of In Vivo Bioavailability and BioequivalenceStudies for Immediate-Release Solid Oral Dosage Forms Based on a Biopharmaceutics Classification System [R] . 2000

机译：工业指南。基于生物药剂学分类系统，立即释放固体口服剂型的体内生物利用度和生物等效性研究的放弃

The pig as a preclinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosage forms: a PEARRL review

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