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use of protein-coupled receptor agonists, but in the treatment of metabolic syndrome, its components and its complications

机译:使用蛋白偶联受体激动剂,但用于治疗代谢综合征,其成分和并发症

摘要

USE OF PROTEIN G-COUPLED RECEPTOR AGONISTS, BUT IN THE TREATMENT OF METABOLIC SYNDROME, COMPONENTS, AND THEIR COMPLICATIONS. The present invention is characterized by the use of protein G-coupled receptor agonists, but as a mechanism of control, prevention and treatment of triglyceride, cholesterol and glucose body levels, as well as arterial hypertension and possible body weight increase, characteristic of the metabolic syndrome and its complications. Another feature of the invention is the use of protein G-coupled receptor agonists, But, including the Angiotensin- (1-7) peptide and its analogs, agonists, peptides or non-peptides as modulators of insulin resistance and insulin intolerance. glucose and the prevention and treatment of related changes. The invention claims the use of protein G-coupled receptor agonists, MAS, formulated with pharmaceutically and pharmacologically acceptable excipients or carriers, and protein G-coupled receptor agonists, but including the Angiotensin- (1-7) peptide and analogs thereof. , agonists, peptides or non-peptides as modulators of the metabolic syndrome, its diseases and their complications.
机译:使用蛋白G偶联的受体激动剂,但可治疗代谢综合征,成分及其并发症。本发明的特征在于使用蛋白G偶联的受体激动剂,但是作为控制,预防和治疗甘油三酸酯,胆固醇和葡萄糖的身体水平以及动脉高血压和可能的体重增加的机制,其是代谢的特征。综合征及其并发症。本发明的另一个特征是使用蛋白G偶联的受体激动剂,但是包括血管紧张素-(1-7)肽及其类似物,激动剂,肽或非肽作为胰岛素抵抗和胰岛素耐受性的调节剂。血糖与防治有关的变化。本发明要求使用与药学和药理学可接受的赋形剂或载体配制的蛋白G偶联的受体激动剂MAS和蛋白G偶联的受体激动剂,但包括血管紧张素-(1-7)肽及其类似物的用途。 ,激动剂,肽或非肽可作为代谢综合征,其疾病及其并发症的调节剂。

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