首页> 外国专利> Antigen Binding Protein that binds to the Receptor of human glucagon; Nucleic Acid encoding; production method; Pharmaceutical composition that comprises; and their use for treating or preventingType 2 diabetes.

Antigen Binding Protein that binds to the Receptor of human glucagon; Nucleic Acid encoding; production method; Pharmaceutical composition that comprises; and their use for treating or preventingType 2 diabetes.

机译:与人胰高血糖素受体结合的抗原结合蛋白;核酸编码;生产方法;药物组合物,其包含;及其在治疗或预防2型糖尿病中的用途。

摘要

The present disclosure provides compositions and methods relating to antigen binding proteins, in particular, antibodies which specifically bind to the human glucagon receptor. The disclosure provides nucleic acids encoding such antigen binding proteins and antibodies and methods of making and using such antibodies including methods of treating and preventing type 2 diabetes and related disorders by administering such antibodies to a subject in need of such treatment.
机译:本公开提供了与抗原结合蛋白,特别是与人胰高血糖素受体特异性结合的抗体有关的组合物和方法。本公开提供了编码此类抗原结合蛋白和抗体的核酸,以及制备和使用此类抗体的方法,包括通过向需要这种治疗的受试者施用此类抗体来治疗和预防2型糖尿病和相关疾病的方法。

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