Compound 3 - 1 - (1 - methyl - 3 - trifluoromethyl - pyridin-3-yl) ethylamino - 5 - (3 - trifluorometoxifenil) - 1 - 4 - (trifluoromethyl) - phenyl) - pyrrolidin-2-one; and use for the treatment of a disorder selected ObesDery, Schizophrenia, Substance Abuse, or depends on

摘要

Compounds and pharmaceutical compositions comprising compounds of the Formula as CB1 receptor inverse agonists useful for reducing body weight in mammals, treating cognitive impairment associated with schizophrenia, and mitigating treatment emergent weight gain observed during treatment with antipsychotics.