首页> 外国专利> Solid dosage form rapidly disintegrating Lyophilized comprising an effective amount of a Thrombin receptor antagonist; and used to treat a patient who is at risk of coNtraer Acute Coronary Syndrome.

Solid dosage form rapidly disintegrating Lyophilized comprising an effective amount of a Thrombin receptor antagonist; and used to treat a patient who is at risk of coNtraer Acute Coronary Syndrome.

机译:冻干的固体剂型迅速崩解,其包含有效量的凝血酶受体拮抗剂;并用于治疗有患急性冠状动脉综合症风险的患者。

摘要

Disclosed is a lyophilized rapidly disintegrating solid dosage form, one embodiment of which comprises a thrombin receptor antagonist such as, or a pharmaceutically acceptable salt or hydrate thereof, a polymer such as gelatin, and a matrix forming agent such as mannitol. Systems for effectively buffering the pre-lyophilized suspension are taught, along with methods of treating patients at risk for acute coronary syndrome by administering such a rapidly disintegrating solid dosage form.
机译:公开了一种冻干的快速崩解固体剂型,其一个实施方案包括凝血酶受体拮抗剂,例如其或其药学上可接受的盐或水合物,聚合物例如明胶,和基质形成剂例如甘露醇。教导了有效缓冲预冻干的悬浮液的系统,以及通过施用这种快速崩解的固体剂型来治疗有急性冠脉综合征风险的患者的方法。

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