Compounds derived from - 2 - (6 - substituted purine and purinona Bencimidazolil); Pharmaceutical composition comprising Said compound and use of the compound in the treatment of autoimmune diseases.Disease, inflammatory disease mediated by M

摘要

The present invention provides novel purinones and purines useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection. The compounds are of the general formulae I and II shown below, in which Q is selected from the group consisting of CX and nitrogen; and A is chosen from the group consisting of H, (C1-C6) alkyl, heteroaryl, and aryl: