首页> 外国专利> Compounds derived from 4,5-dihydro - 2H benzo (e) indazol,Divalent metal Transporter inhibitors - 1 (DMT1); Pharmaceutical composition comprising these Compounds, and use for treating a disorder of Iron.

Compounds derived from 4,5-dihydro - 2H benzo (e) indazol,Divalent metal Transporter inhibitors - 1 (DMT1); Pharmaceutical composition comprising these Compounds, and use for treating a disorder of Iron.

机译:衍生自4,5-二氢-2H苯并(e)吲唑的化合物,二价金属转运体抑制剂-1(DMT1);包含这些化合物的药物组合物,以及用于治疗铁病症的用途。

摘要

This invention is directed to compounds of formula (I): wherein m, RSUP1/SUP, RSUP2/SUP, RSUP3 /SUPand RSUP4 /SUPare as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, for the treatment of iron disorders. This invention is also directed to pharmaceutical compositions comprising the compounds and methods of using the compounds to treat iron disorders.
机译:本发明涉及式(I)的化合物:其中m,R 1 ,R 2 ,R 3 和R 4 如本文所定义,为立体异构体,对映异构体,互变异构体或其混合物;或其药学上可接受的盐,溶剂化物或前药,用于治疗铁症。本发明还涉及包含所述化合物的药物组合物以及使用所述化合物治疗铁疾病的方法。

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