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Spray dry amorphous powder with low residual moisture and excellent storage stability

机译:喷雾干燥的无定形粉末,残留水分低,具有出色的储存稳定性

摘要

The present invention relates to spray-dried amorphous powders which contain a pharmaceutical active substance and a matrix-forming agent, preferably a polymer, sugar or sugar alcohol in an amount of =20-60% (w/w). The powders have a moisture content which is less than 1.2% (w/w), preferably less than 1% (w/w). The present invention also relates to special methods of preparing such powders and methods of administering them by inhalation.
机译:本发明涉及喷雾干燥的无定形粉末,其包含≥20-60%(w / w)的量的药物活性物质和基质形成剂,优选聚合物,糖或糖醇。粉末的水分含量小于1.2%(w / w),优选小于1%(w / w)。本发明还涉及制备这种粉剂的特殊方法和通过吸入给药的方法。

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