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BACTERIAL PACKAGING STRAINS USED FOR GENERATION AND PRODUCTION OF RECOMBINANT NUKLEOKAPSIDES WITH TWO-CELLULAR RNA AND THEIR APPLICATION
BACTERIAL PACKAGING STRAINS USED FOR GENERATION AND PRODUCTION OF RECOMBINANT NUKLEOKAPSIDES WITH TWO-CELLULAR RNA AND THEIR APPLICATION
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机译：用于产生和生产带有两种细胞核糖核酸重组核糖核酸的细菌包装菌株及其应用
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摘要
The present invention relates to bacterial packaging strains that can be used to produce recombinant nucleocapsids containing double-stranded RNA (rdsRN). Packaging strains can be used to produce RNA-encoding vaccine antigens, biologically active proteins, immunoregulatory proteins, antisense RNAs and catalytic RNAs in eukarmotic cells or tissues. Recombinant ssRNA is introduced into strains and packaged until rdsRN de novo is formed.
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机译：本发明涉及细菌包装菌株，其可用于产生含有双链RNA（rdsRN）的重组核衣壳。包装菌株可用于在真核细胞或组织中产生编码RNA的疫苗抗原，生物活性蛋白，免疫调节蛋白，反义RNA和催化RNA。将重组ssRNA引入菌株并包装，直到形成rdsRN de novo。
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