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PHENYL-CONTAINING N-ACYL DERIVATIVES OF AMINES AND AMINO ACIDS, METHOD FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITION AND THEIR APPLICATION

机译:氨基和氨基酸的含苯酚的N-酰基衍生物,其制备方法,药物组成及其应用

摘要

The present invention relates to a new phenyl-containing N-acyl derivative of biogenic amines and amino acids of the general formula I as cyclooxygenase inhibitors having analgesic and anti-inflammatory properties, without side effects, in particular ulcerogenicity and prosasmatic effects, the ability to potentiate the action of other analgesics, which, in addition, have antihypoxic , antidepressant and antiparkinsonian action, as well as to methods for producing new and known phenyl-containing N-ac yl derivatives of biogenic amines, a pharmaceutical composition and an agent containing compounds of general formula I, as well as their use and method of treatment.
机译:本发明涉及作为环加氧酶抑制剂的通式I的生物胺和氨基酸的新的含苯基N-酰基衍生物,其具有止痛和抗炎特性,且无副作用,特别是致溃疡性和促肠溶作用,增强其他止痛药的作用,这些止痛药还具有抗缺氧,抗抑郁和抗帕金森病的作用,以及用于生产新的和已知的生物胺的含苯基N-酰基衍生物的方法,药物组合物和含化合物的药物通式Ⅰ的化合物,以及它们的用途和治疗方法。

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