Use of ezetimibe to the Prevention and Treatment of cholesterol Calculus in the biliary Tract

摘要

The invention shows the use of inhibitors specifically designed for intestinal absorption of 2-azerbaijani cholesterol, in particular ezetimibe (SCH 58235),It completely inhibited protein formation in a dead disease model, a low-fat diet. According to cholesterol calculation, the invention of this technology in the precursor model of lithium disease can predict that selectively blocking the intestinal absorption of cholesterol is an effective treatment for primary prevention and / or treatment of human cholesterol. In turn, as mentioned in the previous section, it can be predicted that in humans, the binding of ezetimibe (SCH 58235) is more likely to inhibit cholesterol liver neosynthesis (HMG CoA reduction inhibitor),They may be more effective than ezetimibe (SCH 58235), just to prevent and / or treat vesicular lithium.