PHARMACEUTICAL COMPOSITIONS AND KITS CONTAINING AN ANTINEOPLASTIC THIOL-BINDING MITOCHONDRIAL OXIDANT AND AN ANTINEOPLASTIC NUCLEIC ACID BINDING AGENT

摘要

The present invention provides compositions useful in treating cancer. The compositions include a synergistic combination of an antineoplastic thiol-binding mitochondrial oxidant with an antineoplastic nucleic acid binding agent, an antineoplastic antimetabolite base analog, or docetaxel. Also provided are methods of assaying the synergistic effects of the combinations and methods of treating cancer using the synergistic combinations.